FDA approves treatment to protect stem cell transplant patients from disease

Pharmacyclics — a subsidiary of the global biopharmaceutical company AbbVie — earned expanded approval for its drug Imbruvica from the Food and Drug Administration Wednesday.

Here are three things to know.

1. The FDA previously approved Imbruvica for the treatment of lymphocytic leukemia.

2. Under the expanded approval, the drug can be used to treat adult patients with chronic graft versus host disease, which occurs when immune cells from donated tissues — often stem cells from donated bone marrow — attack the new host's body cells.

3. Imbruvica is the first FDA-approved therapy for the treatment of chronic graft versus host disease.

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