Nearly a year after launching the online pharmacy Mark Cuban Cost Plus Drug Co., the company has hundreds of generics, more than 1 million customers, and partnerships with pharmacy benefit managers and payers.
Over the next few months, the business — which sells drugs with a $3 pharmacy dispensing fee, $5 shipping fee and a 15 percent profit margin — is working toward offering insulin, developing its Dallas manufacturing plant, collaborating with hospitals to solve ongoing drug shortages and entering the arduous market of brand-name drugs.
As of Dec. 27, its biggest cost reduction is tolvaptan, a generic used to treat low sodium levels in blood, which comes with a markdown of nearly 80 percent.
Here are the top 50 medications with the biggest price cuts from Cost Plus Drug Co.:
1. Tolvaptan (Generic for Samsca)
Retail price: $9,039.90
MCCPDC price: $1,900.50
Savings: $7,139.40
2. Temozolomide (Generic for Temodar)
Retail price: $3,363.60
MCCPDC price: $311.70
Savings: $3,051.90
3. Imatinib (Generic for Gleevec)
Retail price: $2,502.50
MCCPDC price: $14.40
Savings: $2,488.10
4. Deferasirox (Generic for Jadenu)
Retail price: $2,332.80
MCCPDC price: $15
Savings: $2,317.80
5. Aprepitant (Generic for Emend)
Retail price: $2,691.90
MCCPDC price: $522.60
Savings: $2,169.30
6. Dimethyl fumarate (Generic for Tecfidera)
Retail price: $2,176.06
MCCPDC price: $15.08
Savings: $2,160.98
7. Omeprazole-sodium bicarbonate (Generic for Zegerid)
Retail price: $2,072.88
MCCPDC price: $20.10
Savings: $2,052.78
8. Emtricitabine-tenofovir DF (Generic for Truvada)
Retail price: $1,847.41
MCCPDC price: $15.42
Savings: $1,831.99
9. Valganciclovir (Generic for Valcyte)
Retail price: $1,750.43
MCCPDC price: $100.20
Savings: $1,650.23
10. Linezolid (Generic for Zyvox)
Retail price: $1,612.20
MCCPDC price: $32.40
Savings: $1,579.80
11. Dalfampridine ER (Generic for Ampyra)
Retail price: $1,394.30
MCCPDC price: $11.40
Savings: $1,382.90
12. Abiraterone acetate (Generic for Zytiga)
Retail price: $1,093.20
MCCPDC price: $39.60
Savings: $1,053.60
13. Cyclobenzaprine extended release (Generic for Amrix)
Retail price: $1,094.33
MCCPDC price: $53.10
Savings: $1,041.23
14. Abacavir/lamivudine (Generic for Epzicom)
Retail price: $1,096.10
MCCPDC price: $57.60
Savings: $1,038.50
15. Vardenafil HCl (Generic for Levitra)
Retail price: $1,167.90
MCCPDC price: $198.30
Savings: $969.60
16. Entecavir (Generic for Baraclude)
Retail price: $995.75
MCCPDC price: $26.70
Savings: $969.05
17. Flucytosine (Generic for Ancobon)
Retail price: $1,181.63
MCCPDC price: $265.80
Savings: $915.83
18. Doxycycline hyclate (Generic for Acticlate)
Retail price: $843.32
MCCPDC price: $15.90
Savings: $827.42
19. Cinacalcet HCl (Generic for Sensipar)
Retail price: $824.59
MCCPDC price: $11.40
Savings: $813.19
20. Diclofenac sodium (Generic for Voltaren-XR)
Retail price: $853.20
MCCPDC price: $51.25
Savings: $801.95
21. Sirolimus (Generic for Rapamune)
Retail price: $1,080.43
MCCPDC price: $281.01
Savings: $799.42
22. Tenofovir disoproxil fumarate (Generic for Viread)
Retail price: $771.30
MCCPDC price: $18.30
Savings: $753
23. Mesalamine (Generic for Canasa)
Retail price: $766.80
MCCPDC price: $26.70
Savings: $740.10
24. Aripiprazole (Generic for Abilify)
Retail price: $677.80
MCCPDC price: $6
Savings: $671.80
25. Vancomycin (Generic for Vancocin HCl)
Retail price: $679.04
MCCPDC price: $32.10
Savings: $646.94
26. Granisetron HCl (Generic for Kytril)
Retail price: $643.80
MCCPDC price: $27.60
Savings: $616.20
27. Paliperidone ER (Generic for Invega)
Retail price: $635.10
MCCPDC price: $91.50
Savings: $543.60
28. Metformin ER (Generic for Fortamet)
Retail price: $564.47
MCCPDC price: $46.20
Savings: $518.27
29. Atovaquone (Generic for Mepron)
Retail price: $704.38
MCCPDC price: $192.75
Savings: $511.63
30. Moxifloxacin HCl (Generic for Avelox)
Retail price: $491.10
MCCPDC price: $22.80
Savings: $468.30
31. Albendazole (Generic for Albenza)
Retail price: $437.68
MCCPDC price: $33
Savings: $404.68
32. Estradiol Vaginal Estrogen Tablet Insert (Generic for Vagifem)
Retail price: $569.10
MCCPDC price: $165.60
Savings: $403.50
33. Prasugrel HCl (Generic for Effient)
Retail price: $398.10
MCCPDC price: $8.10
Savings: $390
34. Mycophenolate sodium DR (Generic for Myfortic)
Retail price: $363.30
MCCPDC price: $9.60
Savings: $353.70
35. Atomoxetine HCl (Generic for Strattera)
Retail price: $357.60
MCCPDC price: $7.20
Savings: $350.40
36. Solifenacin succinate (Generic for Vesicare)
Retail price: $337.50
MCCPDC price: $5.10
Savings: $332.40
37. Pramipexole dihydrochloride ER (Generic for Mirapex ER)
Retail price: $452.18
MCCPDC price: $129
Savings: $323.18
38. Imiquimod (Generic for Aldara)
Retail price: $337.50
MCCPDC price: $21.90
Savings: $315.60
39. Levofloxacin (Generic for Levaquin)
Retail price: $320.76
MCCPDC price: $7.80
Savings: $312.96
40. Lansoprazole DR orally disintegrating tablets (Generic for Prevacid SoluTab)
Retail price: $403.83
MCCPDC price: $95.40
Savings: $308.43
41. Tadalafil (Generic for Cialis)
Retail price: $306.90
MCCPDC price: $4.50
Savings: $302.40
42. Rizatriptan benzoate (Generic for Maxalt)
Retail price: $311.10
MCCPDC price: $15.30
Savings: $295.80
43. Ofloxacin otic (Generic for Floxin Otic)
Retail price: $287.44
MCCPDC price: $12.75
Savings: $274.69
44. Desvenlafaxine succinate extended release (Generic for Pristiq)
Retail price: $289.53
MCCPDC price: $18.30
Savings: $271.23
45. Oseltamivir (Generic for Tamiflu)
Retail price: $287.70
MCCPDC price: $20.70
Savings: $267
46. Vilazodone HCl (Generic for Viibryd)
Retail price: $285.66
MCCPDC price: $27.60
Savings: $258.06
47. Dofetilide (Generic for Tikosyn)
Retail price: $251.76
MCCPDC price: $8.70
Savings: $243.06
48. Lidocaine (Generic for Xylocaine)
Retail price: $243.61
MCCPDC price: $5.44
Savings: $238.17
49. Fluticasone-salmeterol (Generic for Advair Diskus)
Retail price: $289.50
MCCPDC price: $60.50
Savings: $229
50. Mesalamine DR (Generic for Lialda)
Retail price: $264.30
MCCPDC price: $37.20
Savings: $227.10