3 top execs out at Boston biotech

Akcea Therapeutics, a Boston-based biotechnology company, has replaced three of its top executives.

The company, a majority-owned affiliate of Ionis Pharmaceuticals, announced Sept. 23 the departures of CEO Paula Soteropoulos, President Sarah Boyce and COO Jeff Goldberg, effective immediately. 

Danueb McDevitt, PhD, the chief business officer of Ionis was named interim CEO. The company didn't announce interim replacements for the president or COO. 

The leadership shakeup comes a year after the company launched its first FDA-approved drug, Tegsedi, a treatment for a rare disease called hereditary transthyretin amyloidosis, according to STAT.  

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