10 most expensive drugs in the US

Spinal muscular atrophy treatment Zolgensma's annual price tag of $2,125,000 makes it the most expensive drug in the U.S., according to a list recently published by online drug price comparison platform GoodRx. 

GoodRx published a list of the 20 most expensive drugs in the U.S. Aug. 11, including only medications filled at pharmacies that patients can self-administer on a regular basis. It posted another ranking of the 10 most expensive drugs in the country Aug. 25, including both drugs dispensed at pharmacies and those that must be administered by a healthcare provider.

The 10 most expensive drugs in the U.S. based on their annual list prices: 

1. Zolgensma — $2,125,000 (AveXis)
   
   
2. Myalept — $855,678 (Amryt Pharma)
   
   
3. Luxturna — $850,000 (Spark Therapeutics)
   
   
4. Folotyn — $793,870 (Acrotech Biopharma)
   
   
5. Brineura — $716,040 (BioMarin Pharmaceuticals)
   
   
6. Soliris — $678,392 (Alexion Pharmaceuticals)
   
   
7. Blincyto — $672,968 (Amgen)
   
   
8. Ravicti — $664,092 (Horizon Therapeutics)
   
   
9. Lumizyme — $643,243 (Sanofi Genzyme)
   
   
10. Actimmune — $633,325 (Horizon Therapeutics)