The HHS Office of the Chief Technology Officer and the American Society of Nephrology announced the first 15 winners of the KidneyX Redesign Dialysis competition, which incentivizes the development of products and methods to prevent, diagnose and treat kidney diseases.
Each of the 15 winning teams of Phase One of the challenge received $75,000. They were chosen from 165 applicants, all of whom submitted proposals detailing innovative approaches to the design of artificial kidney devices. The finalists were judged by a panel of nine leaders in the fields of medicine, biomedical science and engineering, and commercialization.
Here are the 15 Phase One winners and a summary of their proposals, per the HHS.
1. University of Alabama: non-invasive, wearable telehealth device to detect thrombosis and monitor vascular access health of arteriovenous fistulas and grafts in hemodialysis patients.
2. Qidni Labs: air removal system for a wearable renal therapy device.
3. Temple University: atomically precise membranes for high-flux and selective removal of blood toxins.
4. Curion Research Corp., University of California Los Angeles and the University of Arkansas: dialysate- and cell-free renal replacement technology.
5. Outset Medical: automated multimodal sensor to improve patient outcomes in hemodialysis.
6. Beth Israel Deaconess and Biosurfaces: drug-eluting electrospun hemodialysis graft.
7. Stanford University: non-invasive venous waveform analysis for volume-directed kidney failure management.
8. Mount Sinai Renal Research Institute: improving intra-dialytic removal of protein-bound uremic toxin removal using binding competitors.
9. The Kidney Project: intracorporeal ultrafiltration system and intracorporeal hemodialysis system.
10. Access for Life: sensor-enabled hemodialysis.
11. Miromatrix Medical: new kidney grafts.
12. University of Michigan: nitric oxide-eluting, disposable hemodialysis catheter insert to prevent infection and thrombosis.
13. Binnovate Digital Health: self-management platform for patients with chronic kidney disease.
14. University of Washington Center for Dialysis Innovation: ambulatory kidney to improve vitality and rethinking dialysis vascular access.
15. Stanford University: utilizing optical interrogation methods for early diagnosis of peritonitis in peritoneal dialysis patients.
Phase Two of the competition, which will begin accepting submissions in the fall, asks applicants to develop functional prototypes that can replicate some or all kidney functions. The three winning teams will receive $500,000 each.
Editor's note: This article was updated May 1 at 11:40 a.m.
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