The Agency for Healthcare Research and Quality's National Guideline Clearinghouse has updated clinical practice guidelines regarding initial urinary tract infection in febrile infants and children aged 2-24 months.
The updated guidelines include seven recommendations for diagnosis and management of UTI in infants and children. The recommendations are accompanied by strength of recommendation, which is based on quality of evidence in medical literature.
For instance, the authors strongly recommend "if a clinician decides that a febrile infant with no apparent source for the fever requires antimicrobial therapy to be administered because of ill appearance or another pressing reason, the clinician should ensure that a urine specimen is obtained for both culture and urinalysis before an antimicrobial agent is administered; the specimen needs to be obtained through catheterization or suprapubic aspiration because the diagnosis of urinary tract infection cannot be established reliably through culture of urine collected in a bag (evidence quality: A; strong recommendation)."
The updated guidelines include seven recommendations for diagnosis and management of UTI in infants and children. The recommendations are accompanied by strength of recommendation, which is based on quality of evidence in medical literature.
For instance, the authors strongly recommend "if a clinician decides that a febrile infant with no apparent source for the fever requires antimicrobial therapy to be administered because of ill appearance or another pressing reason, the clinician should ensure that a urine specimen is obtained for both culture and urinalysis before an antimicrobial agent is administered; the specimen needs to be obtained through catheterization or suprapubic aspiration because the diagnosis of urinary tract infection cannot be established reliably through culture of urine collected in a bag (evidence quality: A; strong recommendation)."
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