Results from a recent study showed that administration of a single antibiotic increased mice's susceptibility to C. difficile, according to research published in Infection and Immunity.
For their study, researchers from Memorial Sloan-Kettering Cancer Center in New York City administered a single dose of clindamycin to a group of mice. Results showed the mice experienced weight loss, diarrhea and colitis and a 40-50 percent higher mortality rate. In addition, surviving mice remained susceptible to C. difficile infection for at least 28 days.
For their study, researchers from Memorial Sloan-Kettering Cancer Center in New York City administered a single dose of clindamycin to a group of mice. Results showed the mice experienced weight loss, diarrhea and colitis and a 40-50 percent higher mortality rate. In addition, surviving mice remained susceptible to C. difficile infection for at least 28 days.
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