Risk of death increases with each day of staph infection, study finds

Every passing day that patients have Staphylococcus aureus bacteremia increases their relative risk of death, a study published in Clinical Infectious Diseases shows.

Researchers conducted a multicenter, observational study of 884 hospitalized adult patients with Staphylococcus aureus bacteremia. They divided patients into three groups based on how long they had Staphylococcus aureus bacteremia:

● Short (one to two days)
● Intermediate (three to six days)
● Prolonged (seven of more days)

Of the 884 patients, 63 percent experienced a short duration of bacteremia; 28 percent experienced an intermediate duration; and 9 percent a prolonged duration.

The study shows the prolonged group had the highest proportion of methicillin-resistant Staphylococcus aureus. Choice of antibiotic therapy did not significantly affect bacteremia duration.

Researchers also found that metastatic complications, length of stay and 30-day mortality worsened as duration of having the bacteremia increased. Each day of bacteremia was associated with relative risk of death of 1.16.

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