Preoperative sepsis is directly correlated to postoperative arterial and venous thrombosis risk, according to an Oncology Practice report.
An analysis of approximately 1.75 million surgical procedures at 314 U.S. hospitals participating in ACS' National Surgical Quality Improvement Project found the higher the severity of a sepsis infection, the higher the risk of a patient experiencing thrombosis following surgery. The results were presented by Jacques Donze, MD, a research associate in the department of medicine at Brigham and Women's Hospital in Boston, at the American College of Cardiology annual meeting.
Sign up for our FREE E-Weekly for more coverage like this sent to your inbox!
Forty-eight hours prior to surgery, 7.8 percent of patients had either systemic inflammatory response syndrome — an early form of sepsis — sepsis or septic shock. These patients had a 4.2 percent postoperative thrombosis rate, compared to 1.2 percent rate for patients without sepsis.
Broken down by severity of sepsis, SIRS patients' risk of thrombosis increased 2.5-fold. Sepsis patients' risk of thrombosis increased approximately 3.3-fold, and septic shock patients' risk of thrombosis increased nearly 6-fold.
Dr. Donze suggests the risk-benefit assessment of surgical procedures should consider the presence of sepsis, according to the report.
More Articles on Sepsis:
Gut Bacteria Linked to Late-Onset Sepsis in Neonates
UC Davis Researchers Develop Sepsis Detection Algorithm
3 Sepsis Treatments Have Similar Survival Rate