NSAIDs May Fight Multidrug-Resistant Bugs

Evidence suggests non-steroidal anti-inflammatory drugs may act against multidrug-resistant organisms, according to research published in Chemistry and Biology.

While studying the effects of NSAIDs on E. coli, researchers observed the drugs prevented activation of genes for DNA replication and repair in the bacteria, destroying the organisms in a completely different way than conventional antibiotics, according to a Forbes report on the study.

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The NSAIDs studied were bromofenac, carprofen and vedaprofen, which are often used in veterinary medicine.

While more research remains, the effect NSAIDs have on bacterial replication may be used as a starting point for creating new, more effective classes of antibiotics in the fight against MDR organisms, according to one of the study's authors quoted in Forbes.

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