Extremely drug-resistant hospital-acquired infections do not lead to higher mortality rates than other HAIs for intensive care unit patients, according to research published in the American Journal of Infection Control.
Researchers identified approximately 100 ICU patients with XDR gram-negative bacterial infections — infections resistant to two or more antibiotics — and compared mortality rates with a control group of ICU patients with infections that were resistant to zero or one antibiotics.
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While XDR infections were more likely in immunocompromised patients as well as patients exposed to the antibiotics amikacin, levofloxacin or trimethoprim-sulfamethoxazole, infection with an XDR strain of bacteria was not independently associated with increased mortality among ICU patients.
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