Infants older than 60 days old experienced a lower infection rate when administered tight glycemic control care following cardiac surgery, but the inverse was true for patients younger than 60 days old, according to a study in Circulation.
Researchers randomly assigned approximately 1,000 infants to either tight glycemic control care or standard care following cardiac surgery.
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Patients older than 60 days in the TGC group experienced 5.0 infections per 1,000 cardiac intensive care unit days, while the standard care group experienced 14.1 infections per 1,000 CICU days.
However, patients younger than 60 days old in the TGC group experienced 13.5 infections per 1,000 CICU days, and the standard care group experienced 3.7 infections per 1,000 CICU days.
Researchers also identified previous cardiac surgery, chromosomal anomaly and delayed sternal closure were independently associated with infection risk following cardiac surgery.
Researchers suggest further analysis of clinical trials is needed to confirm their findings before clinical practices are changed.
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