Hospital-Onset C. diff Increases Costs

Clostridium difficile infection developed in a hospital may increase costs more than $6,000 compared with patients without CDI, according to a study in Infection Control and Hospital Epidemiology.

Researchers examined hospital-onset CDI in adult inpatients at six Pennsylvania hospitals from 2007 to 2008. Compared with patients matched for baseline characteristics, hospital, principal disease group and length of time from admission to onset, patients with hospital-onset CDI had higher mortality, longer length-of-stay and higher cost. The cost for hospital-onset CDI patients was $20,804 compared with $16,634 for patients without the infection.


The authors calculated the attributable effect of hospital-onset CDI as 4.5 percent for mortality, 2.3 days for length-of-stay and $6,117 for cost.

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