University of Hong Kong researchers identified a chemical compound that can help fight methicillin-resistant Staphylococcus aureus, without resorting to antibiotics, according to the South China Morning Post. The researcher published their findings in mBio.
The compound, NP16, inhibits the MRSA-produced staphyloxanthin, which can resist the human immune system. This allows the body to overcome MRSA and mitigate it.
For the study, researchers examined the effects of NP16 in infected mice. They found the use of MP16 caused MRSA bacteria levels to fall by a factor of 10 within a few days. Additionally, they found the compound was not toxic to human cells.
The researchers claim this is the first study to use chemical genetics to treat MRSA, and they are now looking to see if similar approaches could help fight other superbugs, such as drug-resistant E. coli, according to the report.