HAI Antibiotic Resistance Higher Than CDC Says, Study Finds

Increases in antibiotic resistance are greater than what the Center for Disease Control determined in a 2008 report, according to a new article in the journal Antimicrobial Agents and Chemotherapy.

The article cites the authors' analysis of hospital data, which shows unexpectedly high rates of antibiotic resistance in several bacteria, including:

  • A. baumanii to carbapenems, greater than 50 percent (CDC: 11 percent), rendering carbapenems obsolete for treatment.
  • E. coli to third generation cephalosporins, between 8 and 11 percent (CDC: 5 percent)
  • K. pneumonia to third generation cephalosporins, between 20 and 27 percent (CDC: 15 percent)

The article also determines that the Food and Drug Administration's pledge to renew efforts in antibiotic development has fallen short of its goals.

The authors call for "a complete overhaul" of approaches to antibiotic resistance, disease and prevention, according to a digest of the article by ScienceDaily

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