Patients with Enterobacter infections experienced similar outcomes when treated with cefepime and carbapenems, according to a study in Clinical Infectious Diseases.
Researchers found none of the patients who received cefepime for an Enterobacter infection had persistent bacteremia within one day of administering the antibiotic. Twenty-five percent of patients receiving carbapenems still had persistent bacteremia within one day, but multivariable models show there was no association between carbapenem use and the continued infection.
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Additionally, in-hospital mortality rates were similar for the two antibiotic treatments.
Researchers suggest the use of cefepime should be further explored as an alternate to carbapenems when treating Enterobacter infections.
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