Due to the complexity of their care and effects of renal failure, patients with chronic kidney disease experience more adverse events, according to a study published in the Journal of the American Society of Nephrology.
Researchers analyzed the frequency of both class I — patient-reported adverse events — and class II — actionable safety findings — adverse events in chronic kidney disease patients.
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Researchers found 69.3 percent of patients experienced at least one adverse event, either class I or class II. Additionally, 38.2 percent of patients experienced more than one event, and 18 percent experienced at least one event from each class.
Adverse event rates ranged from 2.9 to 57.6 events per 100 patients for class I events and 2.2 to 8.3 events per 100 patients for class II events.
Hypoglycemia was the most common class I event, and high blood potassium was the most common class II event.
Researchers suggest further research is needed to identify a "safety phenotype" for CKD patients and identify patients at the highest risk for adverse events.
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