As scientists work to find therapies to treat COVID-19, many drugs have been tested to see if they can be repurposed to treat the virus.
Here are three that failed:
- AstraZeneca's Calquence — The drugmaker tested its blood cancer drug, Calquence, to see whether it could help hospitalized COVID-19 patients recover. A phase 2 trial showed the drug didn't result in fewer deaths or respiratory failures.
- Novartis' Ilaris — Novartis tested its arthritis drug Ilaris to see whether it could improve survival rates of COVID-19 patients. Clinical trials found the drug didn't show any benefit for the patients.
- Sanofi & Regeneron's Kevzara — The drugmakers' rheumatoid arthritis drug Kevzara was tested to see its anti-inflammatory qualities would help COVID-19 patients, but the drug didn't significantly shorten patients' hospital stays in a study of 420 people.
Several drugs are still in clinical trials testing their benefit against the virus, including an inhaled version of interferon, a drug commonly used to treat multiple sclerosis; AbbVie's rheumatoid arthritis drug Humira; and Eli Lilly's Olumiant, another rheumatoid arthritis drug.