Healthcare companies were featured more than any other sector on Fortune’s 2025 list of America’s most innovative companies, with 63 healthcare companies recognized — including 36 hospitals and health systems.
The list was developed in partnership with Statista and ranks 300 U.S. companies based on product innovation, process innovation and innovation culture. More than 40,000 employees were surveyed between Sept. 11 and Oct. 19 and a panel of 2,500 external experts also evaluated organizations. Combined, the companies featured on the list generated more than $12.6 billion in revenue over the last 12 months.
Below are the hospitals and health systems featured on the 2025 list, along with their rank out of 300, according to Fortune:
35. Houston Methodist
39. Mayo Clinic (Rochester, Minn.)
44. Mass General Brigham (Somerville, Mass.)
64. Cleveland Clinic
66. Duke University Health System (Durham, N.C.)
72. Children’s Healthcare of Atlanta
88. WVU Medicine (Morgantown, W.Va.)
94. The University of Kansas Health System (Kansas City)
125. Baylor Scott & White Health (Dallas)
130. Henry Ford Health (Detroit)
157. Intermountain Health (Salt Lake City)
161. UPMC (Pittsburgh)
172. Akron (Ohio) Children’s
175. Texas Children’s (Houston)
181. HealthPartners (Bloomington, Minn.)
183. Carilion Clinic (Roanoke, Va.)
188. HCA Healthcare (Nashville, Tenn.)
193. Kaiser Permanente (Oakland, Calif.)
198. Hackensack Meridian Health (Edison, N.J.)
200. Ann & Robert H. Lurie Children’s Hospital of Chicago
214. Banner Health (Phoenix)
215. Acadia Healthcare (Franklin, Tenn.)
234. Sanford Health (Sioux Falls, S.D.)
245. Emory Healthcare (Atlanta)
250. Advocate Health (Charlotte, N.C.)
253. Prisma Health (Greenville, S.C.)
258. Atlantic Health System (Morristown, N.J.)
264. OSF HealthCare (Peoria, Ill.)
272. Norton Healthcare (Louisville, Ky.)
277. CoxHealth (Springfield, Mo.)
282. Baptist Health South Florida (Coral Gables, Fla.)
283. MaineHealth (Portland)
284. Essentia Health (Duluth, Minn.)
286. AdventHealth (Altamonte Springs, Fla.)
293. Children’s Hospital Colorado (Aurora)
300. Novant Health (Winston-Salem, N.C.)
Read more about the methodology here.