The 2026 edition of the Forbes 400 — an annual ranking of the richest Americans — included 15 people in healthcare.
The annual list, now in its 45th iteration, was published Sept. 15. Net worths are as of Sept. 4.
To build the list, Forbes reporters met with many list members in person, virtually or by phone, and interviewed employees, asset managers, attorneys, peers and rivals, while also reviewing Securities and Exchange Commission filings, court records and news articles. The valuations account for stakes in public and private companies, real estate, art and other assets, with debt subtracted and money in charitable foundations excluded. Private companies were valued using revenue or profit estimates weighed against comparable public companies, with a 10% liquidity discount applied. Read more about the full methodology here.
Here are the U.S. healthcare billionaires, along with their ranking among the 400, their estimated net worth and a brief personal description, according to Forbes:
32. Thomas Frist Jr. and family — $33.6 billion. A former Air Force flight surgeon, Dr. Frist co-founded Nashville, Tenn.-based HCA Healthcare with his father in 1968.
96. Robert Duggan — $13.4 billion. Mr. Duggan put $63 million into Summit Therapeutics in 2020 and took on the role of co-CEO, steering the oncology-focused biotech’s drug pipeline.
141. Charlie Mills — $11 billion. He chairs Medline, the Illinois-based medical supply company his father and uncle started in 1966.
151. Patrick Soon-Shiong, MD — $10.3 billion. A physician by training, he developed the cancer treatment Abraxane, which found major commercial success treating pancreatic cancer patients.
156. Li Ge — $10.1 billion. He leads Wuxi Apptec as chairman and CEO, a company that supplies research and clinical trial support to drugmakers and biotech firms around the globe.
187. Carl Cook — $8.8 billion. He stepped into the CEO role at Cook Group, his family’s medical device business, following his father Bill Cook’s death in 2011.
241. Ronda Stryker — $7.1 billion. She sits on the board of Stryker Corp., the medical equipment maker her grandfather, the late Homer Stryker, established.
251. John Brown — $6.9 billion. He spent more than three decades at the helm of Stryker Corp. before stepping down as chairman in 2009.
293. Reinhold Schmieding — $5.8 billion. A Michigan native, he launched orthopedic device maker Arthrex in Munich, Germany, in 1981.
311. Andy Mills — $5.5 billion. He has served as a Medline director and previously held the company’s presidency.
325. Jon Stryker — $5.2 billion. He’s the grandson of Stryker Corp.’s founder; the medical equipment company generated $25.2 billion in sales in 2025.
367. Wendy Abrams — $4.7 billion. Her stake in Medline traces back to her father, Jon Mills, and uncle, Jim Mills, who launched the company in 1966.
367. Stewart Rahr — $4.7 billion. He grew pharmaceutical distributor Kinray, which his father started in 1944, before selling the business to Cardinal Health for $1.3 billion in 2010.
375. Keith Dunleavy and family — $4.6 billion. He built healthcare analytics company Inovalon around a cloud-based software model.
396. August Troendle — $4.4 billion. He founded clinical research firm Medpace in Cincinnati in 1992 and still holds roughly a fifth of its shares as CEO.
